Madhusudhan Gowravaram

Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases

Gregory S. Basarab, Günther Kern, John McNulty et al. · Scientific Reports · 2015 · 100 citations · Full text

“Traceless” solid-phase synthesis of furans via 1,3-dipolar cycloaddition reactions of isomünchnones

Madhusudhan Gowravaram, Mark A. Gallop · Tetrahedron Letters · 1997 · 68 citations

Engineering, Organic Chemistry, Chemistry +4

Discovery of Novel DNA Gyrase Inhibiting Spiropyrimidinetriones: Benzisoxazole Fusion with N-Linked Oxazolidinone Substituents Leading to a Clinical Candidate (ETX0914)

Gregory S. Basarab, P. Doig, Vincent Galullo et al. · Journal of Medicinal Chemistry · 2015 · 68 citations

Bioorganic Chemistry, Molecular Biology, Clinical Candidate +20

Inhibition of Matrix Metalloproteinases by Hydroxamates Containing Heteroatom-Based Modifications of the P1' Group

Madhusudhan Gowravaram, Jeffrey S. Johnson, Daniel Delecki et al. · Journal of Medicinal Chemistry · 1995 · 58 citations · Full text

Pharmaceutical Science, Dual Hfs/hnc Inhibitor, Chemical Biology +17

Novel DNA Gyrase Inhibiting Spiropyrimidinetriones with a Benzisoxazole Scaffold: SAR and in Vivo Characterization

Gregory S. Basarab, Patrick Brassil, P. Doig et al. · Journal of Medicinal Chemistry · 2014 · 55 citations · Full text

Pharmaceutical Science, Drug Target, Staphylococcus Aureus +19