Madhusudhan Gowravaram

Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases

Gregory S. Basarab, Günther Kern, John McNulty et al. · Scientific Reports · 2015 · 104 citations · Full text

Medicine, Infectious Diseases, Pharmacology +16

Discovery of Novel DNA Gyrase Inhibiting Spiropyrimidinetriones: Benzisoxazole Fusion with N-Linked Oxazolidinone Substituents Leading to a Clinical Candidate (ETX0914)

Gregory S. Basarab, P. Doig, Vincent Galullo et al. · Journal of Medicinal Chemistry · 2015 · 71 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

“Traceless” solid-phase synthesis of furans via 1,3-dipolar cycloaddition reactions of isomünchnones

Madhusudhan Gowravaram, Mark A. Gallop · Tetrahedron Letters · 1997 · 68 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

Inhibition of Matrix Metalloproteinases by Hydroxamates Containing Heteroatom-Based Modifications of the P1' Group

Madhusudhan Gowravaram, Jeffrey S. Johnson, Daniel Delecki et al. · Journal of Medicinal Chemistry · 1995 · 58 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Novel DNA Gyrase Inhibiting Spiropyrimidinetriones with a Benzisoxazole Scaffold: SAR and in Vivo Characterization

Gregory S. Basarab, Patrick Brassil, P. Doig et al. · Journal of Medicinal Chemistry · 2014 · 56 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16