Mikiyasu Shirai

Interleukin-6/interleukin-21 signaling axis is critical in the pathogenesis of pulmonary arterial hypertension

Takahiro Hashimoto-Kataoka, Naoki Hosen, Takashi Sonobe et al. · Proceedings of the National Academy of Sciences · 2015 · 247 citations · Full text

Hypertension, Lung Inflammation, Immunology +16

Modified forelimb grip strength test detects aging-associated physiological decline in skeletal muscle function in male mice

Hikari Takeshita, Kōichi Yamamoto, Satoko Nozato et al. · Scientific Reports · 2017 · 231 citations · Full text

Muscle Function, Aging, Kinesiology +17

Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway

Reiko Hanada, Hitoshi Teranishi, James T. Pearson et al. · Nature Medicine · 2004 · 211 citations

Neuropeptides, Gastrointestinal Peptide Hormone, Medicine +12

Effects of Adrenomedullin Inhalation on Hemodynamics and Exercise Capacity in Patients With Idiopathic Pulmonary Arterial Hypertension

Noritoshi Nagaya, Shingo Kyotani, Masaaki Uematsu et al. · Circulation · 2004 · 111 citations · Full text

Early Ghrelin Treatment after Myocardial Infarction Prevents an Increase in Cardiac Sympathetic Tone and Reduces Mortality

Daryl O. Schwenke, Takeshi Tokudome, Ichiro Kishimoto et al. · Endocrinology · 2008 · 90 citations · Full text

Hypertension, Heart Failure, Cardiovascular Function +16