Induction of <i>WT1</i> (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression

Akihiro Tsuboi, Tetsuya Taguchi, Tadashi Osaki, +22

Proceedings of the National Academy of Sciences

Cytotoxic T LymphocytesWt1 PeptideImmune RegulationImmunologyImmunodominance +22

CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia

Naoki Hosen, Christopher Y. Park, Naoya Tatsumi, +5

Proceedings of the National Academy of Sciences

EngineeringMixed-phenotype Acute LeukemiaImmunologyImmunotherapyTumor Biology +15

Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin

Ofelia M. Martínez-Estrada, Laura A. Lettice, Abdelkader Essafi, +11

Nature Genetics

Transcriptional RegulationCell LineageDevelopmental BiologyTissue DevelopmentCell Regulation +7

Interleukin-6/interleukin-21 signaling axis is critical in the pathogenesis of pulmonary arterial hypertension

Takahiro Hashimoto-Kataoka, Naoki Hosen, Takashi Sonobe, +16

Proceedings of the National Academy of Sciences

HypertensionLung InflammationImmunologyPathologyPulmonary Hypertension +14

The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia

Hiroyasu Ogawa, Hiroya Tamaki, Kazuhiro Ikegame, +12

Blood

Overexpression of the Wilms' tumor gene <i>WT1</i> in <i>de novo</i> lung cancers

Yusuke Oji, Shinichiro Miyoshi, Hajime Maeda, +22

International Journal of Cancer

Transcriptional Profiling of Antigen-Dependent Murine B Cell Differentiation and Memory Formation

Deepta Bhattacharya, Ming T. Cheah, Christopher B. Franco, +4

The Journal of Immunology

The activated conformation of integrin β7 is a novel multiple myeloma–specific target for CAR T cell therapy

Naoki Hosen, Yukiko Matsunaga, Kana Hasegawa, +30

Nature Medicine

Cancer ImmunosurveillanceImmunologyCellular Immune ResponseIntegrin β7Immunotherapy +3

Wilms tumor gene peptide-based immunotherapy for patients with overt Leukemia from myelodysplastic syndrome (MDS) or MDS with myelofibrosis

Akihiro Tsuboi, Masaki Murakami, Manabu Hirai, +14

International Journal of Hematology

Hematological MalignancyMyelodysplastic SyndromeMedicineMixed-phenotype Acute LeukemiaHematology +9

Overexpression of the Wilms' tumor gene <i>WT1</i> in primary astrocytic tumors

Yusuke Oji, Tsuyoshi Suzuki, Yoko Nakano, +18

Cancer Science