Potent selective inhibitors of protein kinase C

Peter D. Davis, Christopher H. Hill, Elizabeth Keech, +6

FEBS Letters

InflammationCytokineMedicinal ChemistrySignal TransductionProtein Kinase C +13

Inhibitors of protein kinase C. 2. Substituted bisindolylmaleimides with improved potency and selectivity

Peter D. Davis, Lucy H. Elliott, William R. Harris, +7

Journal of Medicinal Chemistry

Inhibitors of protein kinase C. 1. 2,3-bisarylmaleimides

Peter D. Davis, Christopher H. Hill, Geoffrey Lawton, +5

Journal of Medicinal Chemistry

Combinatorial ChemistryMolecular PharmacologyMedicinal ChemistryBioorganic ChemistryProtein Kinase C +13

Inhibitors of protein kinase C. 3. Potent and highly selective bisindolylmaleimides by conformational restriction

Rino A. Bit, Peter D. Davis, Lucy H. Elliott, +10

Journal of Medicinal Chemistry

Combinatorial ChemistryImmunologyMolecular BiologyPharmacotherapySelective Bisindolylmaleimides +22

The design and synthesis of the Angiotensin Converting Enzyme inhibitor Cilazapril and related bicyclic compounds

Michael R. Attwood, Cedric H. Hassall, Antonin Kröhn, +2

Journal of the Chemical Society Perkin Transactions 1

Combinatorial ChemistryPharmacotherapyChemical BiologyPharmaceutical ChemistryMedicinal Chemistry +14

K252a is a potent and selective inhibitor of phosphorylase kinase

Lucy H. Elliott, Sandra E. Wilkinson, Anthony D. Sedgwick, +4

Biochemical and Biophysical Research Communications

Molecular PharmacologySignal TransductionSignaling PathwayNatural SciencesMolecular Biology +6

A novel conformationally restricted protein kinase C inhibitor, Ro 31‐8425, inhibits human neutrophil superoxide generation by soluble, particulate and post‐receptor stimuli

Robert E. Muid, M.Maureen Dale, Peter D. Davis, +8

FEBS Letters

New potent inhibitors of angiotensin converting enzyme

Michael R. Attwood, RJ Francis, Cedric H. Hassall, +6

FEBS Letters

Potent collagenase inhibitors prevent interleukin-1-induced cartilage degradation in vitro.

John Nixon, K M K Bottomley, Michael J. Broadhurst, +6

PubMed

Tissue EngineeringImmunologyMusculoskeletal ResearchRegenerative MedicineInflammation +17

Inhibition of bovine nasal cartilage degradation by selective matrix metalloproteinase inhibitors

K M K Bottomley, Neera Borkakoti, D. Bradshaw, +16

Biochemical Journal

Laboratory ImmunologyImmunologyGlycobiologyImmunotherapyMusculoskeletal Research +17