Inhibitors of protein kinase C. 2. Substituted bisindolylmaleimides with improved potency and selectivity

Peter D. Davis, Lucy H. Elliott, William R. Harris, +7

Journal of Medicinal Chemistry

Inhibitors of protein kinase C. 3. Potent and highly selective bisindolylmaleimides by conformational restriction

Rino A. Bit, Peter D. Davis, Lucy H. Elliott, +10

Journal of Medicinal Chemistry

Combinatorial ChemistryImmunologyMolecular BiologyPharmacotherapySelective Bisindolylmaleimides +22

Ro 32‐3555, an orally active collagenase inhibitor, prevents cartilage breakdown <i>in vitro</i> and <i>in vivo</i>

E. J. Lewis, Joshua D. Bishop, K M K Bottomley, +12

British Journal of Pharmacology

Ro 32-0432, a selective and orally active inhibitor of protein kinase C prevents T-cell activation.

A M Birchall, J Bishop, D. Bradshaw, +7

Journal of Pharmacology and Experimental Therapeutics

K252a is a potent and selective inhibitor of phosphorylase kinase

Lucy H. Elliott, Sandra E. Wilkinson, Anthony D. Sedgwick, +4

Biochemical and Biophysical Research Communications

Molecular PharmacologySignal TransductionSignaling PathwayNatural SciencesMolecular Biology +6

A novel conformationally restricted protein kinase C inhibitor, Ro 31‐8425, inhibits human neutrophil superoxide generation by soluble, particulate and post‐receptor stimuli

Robert E. Muid, M.Maureen Dale, Peter D. Davis, +8

FEBS Letters

Inhibition of bovine nasal cartilage degradation by selective matrix metalloproteinase inhibitors

K M K Bottomley, Neera Borkakoti, D. Bradshaw, +16

Biochemical Journal

Laboratory ImmunologyImmunologyGlycobiologyImmunotherapyMusculoskeletal Research +17

Subcellular localization of newly incorporated myosin in rabbit fast skeletal muscle undergoing stimulation-induced type transformation

L. L. Franchi, Alan D. Murdoch, Wendy E. Brown, +3

Journal of Muscle Research and Cell Motility

Muscle FunctionMolecular PhysiologySkeletal MusclePhysiologySubcellular Localization +7

Structural Characterisation of Non-Deamidated Acidic Variants of Erwinia chrysanthemi L-asparaginase Using Small-Angle X-ray Scattering and Ion-Mobility Mass Spectrometry

David Gervais, Darryl King, Patrick Kanda, +10

Pharmaceutical Research

Non-deamidated Acidic VariantsMicrobial ProteomicsMass SpectrometryMicrobiologyMedicine +2

Oral, anti-inflammatory activity of a potent, selective, protein kinase C inhibitor

Michael J. Mulqueen, D. Bradshaw, Peter D. Davis, +10

Inflammation Research

InflammationMedicinal ChemistryAnti-inflammatoryMedicineImmunology +6