K M K Bottomley

Ro 32‐3555, an orally active collagenase inhibitor, prevents cartilage breakdown <i>in vitro</i> and <i>in vivo</i>

E. J. Lewis, Joshua D. Bishop, K M K Bottomley et al. · British Journal of Pharmacology · 1997 · 135 citations · Full text

Inhibition of bone resorption <i>in vitro</i> by selective inhibitors of gelatinase and collagenase

P Hill, Andrew Docherty, K M K Bottomley et al. · Biochemical Journal · 1995 · 98 citations · Full text

Tissue Engineering, Sclerostin, Engineering +16

Ro 32-3555, an orally active collagenase selective inhibitor, prevents structural damage in the STR/ORT mouse model of osteoarthritis

Michael Brewster, Jonathan Lewis, Kevin L. Wilson et al. · Arthritis & Rheumatism · 1998 · 82 citations

Potent collagenase inhibitors prevent interleukin-1-induced cartilage degradation in vitro.

John Nixon, K M K Bottomley, Michael J. Broadhurst et al. · PubMed · 1991 · 51 citations

Tissue Engineering, Immunology, Musculoskeletal Research +19

Inhibition of bovine nasal cartilage degradation by selective matrix metalloproteinase inhibitors

K M K Bottomley, Neera Borkakoti, D. Bradshaw et al. · Biochemical Journal · 1997 · 44 citations · Full text

Laboratory Immunology, Immunology, Glycobiology +19