DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway

Joo-Young Im, Kang-Woo Lee, Jong‐Min Woo, +2

Human Molecular Genetics

Reductive StressSignal TransductionNrf2 PathwayDisease MechanismImmunology +10

Enhanced Phosphatase Activity Attenuates α-Synucleinopathy in a Mouse Model

Kang-Woo Lee, Walter W. Chen, Eunsung Junn, +12

Journal of Neuroscience

Serine 129Synaptic TransmissionSynaptic SignalingSocial SciencesDegenerative Pathology +18

Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action

Kyoung‐Shim Kim, Ko-Woon Lee, Kang-Woo Lee, +6

Proceedings of the National Academy of Sciences

Cyclooxygenase-2-dependent neuronal death proceeds via superoxide anion generation

Joo-Young Im, Do-Yeun Kim, Sang‐Gi Paik, +1

Free Radical Biology and Medicine

Superoxide Anion GenerationMedicineApoptosisCell DeathNeuroprotection +5

Apoptosis Signal-Regulating Kinase 1 Mediates MPTP Toxicity and Regulates Glial Activation

Kang-Woo Lee, Xin Zhao, Joo-Young Im, +8

PLoS ONE

Progressive neuronal loss and behavioral impairments of transgenic C57BL/6 inbred mice expressing the carboxy terminus of amyloid precursor protein

Kang-Woo Lee, Joo-Young Im, Jin‐Sook Song, +8

Neurobiology of Disease

Neurodegenerative DiseasesAlzheimer's DiseaseMolecular NeuroscienceProgressive Neuronal LossDegenerative Pathology +10

Behavioral stress causes mitochondrial dysfunction via ABAD up-regulation and aggravates plaque pathology in the brain of a mouse model of Alzheimer disease

Ji‐Seon Seo, Kang-Woo Lee, Taekyung Kim, +3

Free Radical Biology and Medicine

Alzheimer's DiseaseAgingMitochondrial DysfunctionDementiaPhysiology +11

p300 cooperates with c-Jun and PARP-1 at the p300 binding site to activate RhoB transcription in NSC126188-mediated apoptosis

Bo‐Kyung Kim, Joo-Young Im, Gyoonhee Han, +7

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Transcriptional RegulationSignal TransductionSignaling PathwayCell RegulationApoptosis +8

Analysis of differential plaque depositions in the brains of Tg2576 and Tg-APPswe/PS1dE9 transgenic mouse models of Alzheimer disease

Taekyung Kim, Jung Eun Lee, Sun Kyu Park, +8

Experimental & Molecular Medicine