PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease

Joo‐Ho Shin, Han Seok Ko, Ho Chul Kang, +6

Cell

Neurodegenerative DiseasesMolecular NeurosciencePgc-1α ContributesDegenerative PathologyNeurology +6

Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease

Byoung Dae Lee, Joo‐Ho Shin, Jackalina VanKampen, +9

Nature Medicine

MedicineAutophagyDegenerative PathologySystems BiologyPharmacology +2

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage

Ho Chul Kang, Yun-Il Lee, Joo‐Ho Shin, +9

Proceedings of the National Academy of Sciences

Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration

Daniel A. Stevens, Yunjong Lee, Ho Chul Kang, +9

Proceedings of the National Academy of Sciences

MitophagyParis-dependent DeclinesDopamine NeuronsSynaptic SignalingSocial Sciences +24

Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss

Yunjong Lee, Senthilkumar S. Karuppagounder, Joo‐Ho Shin, +11

Nature Neuroscience

Molecular NeurosciencePhysiologyNeurotransmitterNeuroscienceDopamine +1

CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity

Han Seok Ko, Rachel M. Bailey, Wanli W. Smith, +11

Proceedings of the National Academy of Sciences

PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival

Yunjong Lee, Daniel A. Stevens, Sung-Ung Kang, +18

Cell Reports

Human papillomavirus E5 protein induces expression of the EP4 subtype of prostaglandin E2 receptor in cyclic AMP response element-dependent pathways in cervical cancer cells

Jung‐Min Oh, Su-Hyeong Kim, Yun-Il Lee, +5

Carcinogenesis

Signaling PathwayCervical CancerProstaglandin E2 ReceptorCervical Cancer CellsImmunology +11

Protein Microarray Characterization of the S-Nitrosoproteome

Yun-Il Lee, Daniel Giovinazzo, Ho Chul Kang, +12

Molecular & Cellular Proteomics

Cdc42-dependent Mediation of UV-induced p38 Activation by G Protein βγ Subunits

Mi-Ran Seo, Chin-Ho Cho, Yun-Il Lee, +5

Journal of Biological Chemistry

Molecular RegulationApoptosisImmunologyMolecular BiologyCell Death +21