Pierre-Yves Desprez

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

Remi-Martin Laberge, Yu Sun, Arturo V. Orjalo et al. · Nature Cell Biology · 2015 · 1.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen

Jean-Philippe Coppé, Christopher K. Patil, Françis Rodier et al. · PLoS ONE · 2010 · 446 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

<i>Id-1</i> as a molecular target in therapy for breast cancer cell invasion and metastasis

Sylvia Fong, Yoko Itahana, Tomoki Sumida et al. · Proceedings of the National Academy of Sciences · 2003 · 204 citations · Full text

Medicine, Cancer Biology, Oncology +16

Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging

Denise P. Muñoz, Steven M. Yannone, Anneleen Daemen et al. · JCI Insight · 2019 · 154 citations · Full text

Medicine, Immunology, Oncology +17

Transforming Growth Factor-β Can Suppress Tumorigenesis through Effects on the Putative Cancer Stem or Early Progenitor Cell and Committed Progeny in a Breast Cancer Xenograft Model

Binwu Tang, Naomi Yoo, Mary Vu et al. · Cancer Research · 2007 · 96 citations · Full text

Medicine, Cell Biology, Oncology +17