Arturo V. Orjalo

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

Remi-Martin Laberge, Yu Sun, Arturo V. Orjalo et al. · Nature Cell Biology · 2015 · 1.1K citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +8

Cell surface-bound IL-1α is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network

Arturo V. Orjalo, Dipa Bhaumik, Bridget K. Gengler et al. · Proceedings of the National Academy of Sciences · 2009 · 603 citations · Full text

MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8

Dipa Bhaumik, Gary K. Scott, Shiruyeh Schokrpur et al. · Aging · 2009 · 474 citations · Full text

Aging, Il-6 Secretion, Immunology +17

Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination

Je‐Hyun Yoon, Kotb Abdelmohsen, Jiyoung Kim et al. · Nature Communications · 2013 · 452 citations · Full text

Chromatin, Protein Folding, Natural Sciences +10

Depletion of cellular polyamines, spermidine and spermine, causes a total arrest in translation and growth in mammalian cells

Swati Mandal, Ajeet Mandal, Hans E. Johansson et al. · Proceedings of the National Academy of Sciences · 2013 · 282 citations · Full text

Fertility, Molecular Regulation, Cellular Spermidine +19