Joseph T. Blake

Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins

Shinjiro Odake, Chih Min Kam, Lakshmi Narasimhan et al. · Biochemistry · 1991 · 248 citations

Life Sciences, Biochemistry, Immunology +15

Voltage-gated potassium channels regulate calcium-dependent pathways involved in human T lymphocyte activation.

C. Shirley Lin, Robert C. Boltz, Joseph T. Blake et al. · The Journal of Experimental Medicine · 1993 · 240 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Blockade of the voltage-gated potassium channel Kv1.3 inhibits immune responses in vivo

G C Koo, Joseph T. Blake, Althea Talento et al. · The Journal of Immunology · 1997 · 219 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Human cytotoxic lymphocyte granzyme B. Its purification from granules and the characterization of substrate and inhibitor specificity.

Martin Poe, Joseph T. Blake, David A. Boulton et al. · Journal of Biological Chemistry · 1991 · 192 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Correolide and Derivatives Are Novel Immunosuppressants Blocking the Lymphocyte Kv1.3 Potassium Channels

Gloria C. Koo, Joseph T. Blake, Kashmira Shah et al. · Cellular Immunology · 1999 · 81 citations

Medicine, Immunology, Pharmacology +14