A multiplicity of CCAAT box-binding proteins

Arnulf Dorn, Jacques Bollekens, Adrian Staub, +2

Cell

Protein FunctionSignal TransductionProtein AssemblyBiochemistryNatural Sciences +3

Identification of an antimalarial synthetic trioxolane drug development candidate

Jonathan L. Vennerstrom, Sarah Arbe‐Barnes, Reto Brun, +16

Nature

Antiparasitic AgentPharmacologyPharmacotherapyDrug DevelopmentMedicine +2

An Assessment of Drug-Haematin Binding as a Mechanism for Inhibition of Haematin Polymerisation by Quinoline Antimalarials

Arnulf Dorn, Sudha Rani Vippagunta, Hugues Matile, +3

Biochemical Pharmacology

Quinoline AntimalarialsAntiparasitic AgentMedicineDrug-haematin BindingMalaria +6

Structural Specificity of Chloroquine−Hematin Binding Related to Inhibition of Hematin Polymerization and Parasite Growth

Sudha Rani Vippagunta, Arnulf Dorn, Hugues Matile, +5

Journal of Medicinal Chemistry

Spiro and Dispiro-1,2,4-trioxolanes as Antimalarial Peroxides:  Charting a Workable Structure−Activity Relationship Using Simple Prototypes

Yuxiang Dong, Jacques Chollet, Hugues Matile, +15

Journal of Medicinal Chemistry

The Structure−Activity Relationship of the Antimalarial Ozonide Arterolane (OZ277)

Yuxiang Dong, Sergio Wittlin, K. Sriraghavan, +17

Journal of Medicinal Chemistry

Medicinal ChemistryBiochemistryAntiparasitic AgentMedicineStructure−activity Relationship +12

8-Aminoquinolines Active against Blood Stage <i>Plasmodium falciparum</i> In Vitro Inhibit Hematin Polymerization

Jonathan L. Vennerstrom, Edwin O. Nuzum, Robert E. Miller, +6

Antimicrobial Agents and Chemotherapy

A Comparison and Analysis of Several Ways to Promote Haematin (Haem) Polymerisation and an Assessment of Its Initiation In Vitro

Arnulf Dorn, Sudha Rani Vippagunta, Hugues Matile, +3

Biochemical Pharmacology

Regenerative MedicineHematologyBiomedical EngineeringSeveral Ways

Hematin Polymerization Assay as a High-Throughput Screen for Identification of New Antimalarial Pharmacophores

Yae Kurosawa, Arnulf Dorn, Michiko Kitsuji-Shirane, +7

Antimicrobial Agents and Chemotherapy

Evaluation of a High-Throughput Fluorescence Assay Method for hERG Potassium Channel Inhibition

Arnulf Dorn, Francis Hermann, Andreas Ebneth, +4

SLAS DISCOVERY