Yuxiang Dong

Identification of an antimalarial synthetic trioxolane drug development candidate

Jonathan L. Vennerstrom, Sarah Arbe‐Barnes, Reto Brun et al. · Nature · 2004 · 613 citations

Antiparasitic Agent, Pharmacology, Pharmacotherapy +4

Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria

Susan A. Charman, Sarah Arbe‐Barnes, Ian Bathurst et al. · Proceedings of the National Academy of Sciences · 2011 · 374 citations · Full text

Antiparasitic Agent, Malaria, Pharmacology +13

In Vitro and In Vivo Activities of Synthetic Trioxolanes against Major Human Schistosome Species

Shu-Hua Xiao, Jennifer Keiser, Jacques Chollet et al. · Antimicrobial Agents and Chemotherapy · 2007 · 182 citations · Full text

Spiro and Dispiro-1,2,4-trioxolanes as Antimalarial Peroxides:  Charting a Workable Structure−Activity Relationship Using Simple Prototypes

Yuxiang Dong, Jacques Chollet, Hugues Matile et al. · Journal of Medicinal Chemistry · 2005 · 117 citations

Relationship between Antimalarial Activity and Heme Alkylation for Spiro- and Dispiro-1,2,4-Trioxolane Antimalarials

Darren J. Creek, William N. Charman, Francis C. K. Chiu et al. · Antimicrobial Agents and Chemotherapy · 2008 · 108 citations · Full text

Heme Alkylation, Phytoalexin, Medicinal Chemistry +15