Synthesis, cytotoxicity, and antiviral activities of new neolignans related to honokiol and magnolol

Franck Amblard, Baskaran Govindarajan, Benjamin Lefkove, +4

Bioorganic & Medicinal Chemistry Letters

Antiviral CompoundNew NeolignansMedicinePhytopharmacologyAntiviral Activities +4

Pre-steady-state Kinetic Studies Establish Entecavir 5′-Triphosphate as a Substrate for HIV-1 Reverse Transcriptase

Robert A. Domaoal, Moira A. McMahon, Chloe L. Thio, +8

Journal of Biological Chemistry

Synthesis, Antiviral Activity, and Mechanism of Drug Resistance of <scp>d</scp>- and <scp>l</scp>-2‘,3‘-Didehydro-2‘,3‘-dideoxy-2‘-fluorocarbocyclic Nucleosides

Jianing Wang, Yunho Jin, Kimberly L. Rapp, +3

Journal of Medicinal Chemistry

Differential induction of interleukin-I β mRNA in the brain parenchyma of Lewis and Fischer rats after peripheral injection of lipopolysaccharides

Leonardo H. Tonelli, Shigeru Maeda, Kimberly L. Rapp, +1

Journal of Neuroimmunology

InflammationCytokineAnti-inflammatoryPeripheral InjectionMedicine +9

<scp>d</scp>- and <scp>l</scp>-2‘,3‘-Didehydro-2‘,3‘-dideoxy-3‘-fluoro-carbocyclic Nucleosides:  Synthesis, Anti-HIV Activity and Mechanism of Resistance

Jianing Wang, Yunho Jin, Kimberly L. Rapp, +2

Journal of Medicinal Chemistry

5′-O-Aliphatic and amino acid ester prodrugs of (−)-β-d-(2R,4R)-dioxolane-thymine (DOT): Synthesis, anti-HIV activity, cytotoxicity and stability studies

Yuzeng Liang, Ashoke Sharon, Jason Grier, +3

Bioorganic & Medicinal Chemistry

Medicinal ChemistryAnti-hiv ActivityPharmaceutical ScienceBiochemistryMedicine +9

Comparative analysis of in vitro processivity of HIV-1 reverse transcriptases containing mutations 65R, 74V, 184V and 65R+74V

Prem Lal Sharma, James H. Nettles, Anya Feldman, +2

Antiviral Research

Vitro ProcessivityViral ReplicationMolecular VirologyHiv-1 Reverse TranscriptasesNatural Sciences +9

Synthesis and anti-HIV activity of 5-haloethynyl and 5-(1,2-dihalo)vinyl analogues of AZT and FLT

Nicolas Joubert, Franck Amblard, Kimberly L. Rapp, +2

Tetrahedron

Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: Antiviral activity and cellular toxicity

Vanessa Escuret, Vincent Aucagne, Nicolas Joubert, +5

Bioorganic & Medicinal Chemistry

HalogenationAntiviral ActivityCellular ToxicityOrganic ChemistryVinyluracil Nucleosides +4

Synthesis, antiviral activity, and stability of nucleoside analogs containing tricyclic bases

Franck Amblard, Emilie Fromentin, Mervi Detorio, +6

European Journal of Medicinal Chemistry

EngineeringAntiviral ActivityNucleic Acid BiochemistryAntiviral Drug DevelopmentAntiviral Therapy +8