Honokiol, a Small Molecular Weight Natural Product, Inhibits Angiogenesis in Vitro and Tumor Growth in Vivo

Xianhe Bai, Francesca Cerimele, Masuko Ushio‐Fukai, +11

Journal of Biological Chemistry

Mitogen-actived protein kinase activation is an early event in melanoma progression.

C. M. S. Cohen, Ángel Zavala-Pompa, Judy Sequeira, +7

PubMed

Overexpression of Akt converts radial growth melanoma to vertical growth melanoma

Baskaran Govindarajan, James E. Sligh, Bethaney Vincent, +15

Journal of Clinical Investigation

Vertical Growth MelanomaCell RegulationSkin CancerRadial Growth MelanomaRadial Growth +13

Reactive Oxygen-induced Carcinogenesis Causes Hypermethylation of p16Ink4a and Activation of MAP Kinase

Baskaran Govindarajan, Robert Klafter, Mark Steven Miller, +5

Molecular Medicine

Malignant Transformation of Melanocytes to Melanoma by Constitutive Activation of Mitogen-activated Protein Kinase Kinase (MAPKK) Signaling

Baskaran Govindarajan, Xianhe Bai, C. M. S. Cohen, +5

Journal of Biological Chemistry

Pharmacologic Blockade of Angiopoietin-2 Is Efficacious against Model Hemangiomas in Mice

Betsy N. Perry, Baskaran Govindarajan, Sulochana S. Bhandarkar, +14

Journal of Investigative Dermatology

Pharmacologic BlockadeAngiogenesisMedicineHematologyAngiopoietin-2 Is Efficacious +6

Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice

Sulochana S. Bhandarkar, Marisa Jaconi, Levi Fried, +14

Journal of Clinical Investigation

Lipid PeroxidationBend CellsHemangioma GrowthRedox BiologyHuman Hemangiomas +15

Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis

Jack L. Arbiser, Tweeny R. Kau, Martha Konar, +16

Blood

The antidepressant sertraline downregulates Akt and has activity against melanoma cells

Kalpana K. Reddy, Benjamin Lefkove, Lan Bo Chen, +8

Pigment Cell & Melanoma Research

Psychotropic MedicationImmunologyPsychopharmacologyCell DeathPharmacotherapy +18

Carbazole Is a Naturally Occurring Inhibitor of Angiogenesis and Inflammation Isolated from Antipsoriatic Coal Tar

Jack L. Arbiser, Baskaran Govindarajan, Traci E. Battle, +12

Journal of Investigative Dermatology

Occurring InhibitorMedicinePathologyAntipsoriatic Coal TarPharmacotherapy +5