Yunho Jin

Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro-<i>N</i>2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-<i>N</i>4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials

Thomas H. Marsilje, Wei Pei, Bei Chen et al. · Journal of Medicinal Chemistry · 2013 · 405 citations · Full text

Chemoprevention Strategy, Pharmacotherapy, Structure–activity Relationships +21

Discovery of EGFR Selective 4,6-Disubstituted Pyrimidines from a Combinatorial Kinase-Directed Heterocycle Library

Qiong Zhang, Yi Liu, Feng Gao et al. · Journal of the American Chemical Society · 2006 · 60 citations

Combinatorial Chemistry, First Receptor Tyrosine, Tyrosine Kinase +18

Tuning a Protein‐Labeling Reaction to Achieve Highly Site Selective Lysine Conjugation

Grace H. Pham, Weijia Ou, Badry Bursulaya et al. · ChemBioChem · 2018 · 45 citations

Protein Chemistry, Single Lysine, Biochemistry +11

Inhibitory effect of ginsenoside Rg3 on cancer stemness and mesenchymal transition in breast cancer via regulation of myeloid-derived suppressor cells

Joong‐Hyun Song, Da‐Young Eum, Soon-Yong Park et al. · PLoS ONE · 2020 · 37 citations · Full text

Breast Oncology, Cancer Stemness, Health Sciences +13

Role of melatonin combined with exercise as a switch-like regulator for circadian behavior in advanced osteoarthritic knee

Yunkyung Hong, Hyunsoo Kim, Seung‐Hoon Lee et al. · Oncotarget · 2017 · 36 citations · Full text