Eriko Okawa

Dysregulation of intracellular copper homeostasis is common to transgenic mice expressing human mutant superoxide dismutase-1s regardless of their copper-binding abilities

Eiichi Tokuda, Eriko Okawa, Shunsuke Watanabe et al. · Neurobiology of Disease · 2013 · 79 citations · Full text

Biochemistry, Natural Sciences, Metalloprotein +11

Dysregulation of intracellular copper trafficking pathway in a mouse model of mutant copper/zinc superoxide dismutase‐linked familial amyotrophic lateral sclerosis

Eiichi Tokuda, Eriko Okawa, Shin‐ichi Ono · Journal of Neurochemistry · 2009 · 66 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Bioactive Metal +13

Ammonium tetrathiomolybdate delays onset, prolongs survival, and slows progression of disease in a mouse model for amyotrophic lateral sclerosis

Eiichi Tokuda, Shin-ichi Ono, Kumiko Ishige et al. · Experimental Neurology · 2008 · 66 citations

Ammonium Tetrathiomolybdate Delays, Amyotrophic Lateral Sclerosis, Neurochemical Biomarkers +7

Overexpression of metallothionein-I, a copper-regulating protein, attenuates intracellular copper dyshomeostasis and extends lifespan in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase-1

Eiichi Tokuda, Eriko Okawa, Shunsuke Watanabe et al. · Human Molecular Genetics · 2013 · 48 citations

Amyotrophic Lateral Sclerosis, Biochemistry, Natural Sciences +13

Regulation of Intracellular Copper by Induction of Endogenous Metallothioneins Improves the Disease Course in a Mouse Model of Amyotrophic Lateral Sclerosis

Eiichi Tokuda, Shunsuke Watanabe, Eriko Okawa et al. · Neurotherapeutics · 2015 · 28 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Bioactive Metal +9