Shin-ichi Ono

Dysregulation of intracellular copper homeostasis is common to transgenic mice expressing human mutant superoxide dismutase-1s regardless of their copper-binding abilities

Eiichi Tokuda, Eriko Okawa, Shunsuke Watanabe et al. · Neurobiology of Disease · 2013 · 79 citations · Full text

Biochemistry, Natural Sciences, Metalloprotein +11

Metallothionein proteins expression, copper and zinc concentrations, and lipid peroxidation level in a rodent model for amyotrophic lateral sclerosis

Eiichi Tokuda, Shin-ichi Ono, Kumiko Ishige et al. · Toxicology · 2006 · 75 citations

Amyotrophic Lateral Sclerosis, Zinc Concentrations, Bioactive Metal +9

Ammonium tetrathiomolybdate delays onset, prolongs survival, and slows progression of disease in a mouse model for amyotrophic lateral sclerosis

Eiichi Tokuda, Shin-ichi Ono, Kumiko Ishige et al. · Experimental Neurology · 2008 · 66 citations

Ammonium Tetrathiomolybdate Delays, Amyotrophic Lateral Sclerosis, Neurochemical Biomarkers +7

Regulation of Intracellular Copper by Induction of Endogenous Metallothioneins Improves the Disease Course in a Mouse Model of Amyotrophic Lateral Sclerosis

Eiichi Tokuda, Shunsuke Watanabe, Eriko Okawa et al. · Neurotherapeutics · 2015 · 28 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Bioactive Metal +9

Regional brain distribution of metallothionein, zinc and copper in toxic milk mutant and transgenic mice

Shin-ichi Ono, James Koropatnick, M.George Cherian · Toxicology · 1997 · 28 citations

Neurophysiology, Medicine, Metalloprotein +10