Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene

Robert S. Jackson, John W.M. Creemers, Shinya Ohagi, +4

Nature Genetics

ObesityMetabolic SyndromeEnergy HomeostasisMetabolic DisorderGenetics +8

The new enzymology of precursor processing endoproteases.

Donald F. Steiner, Steven P. Smeekens, Shinya Ohagi, +1

Journal of Biological Chemistry

Precursor Processing EndoproteasesBiotransformationCellular EnzymologyBiochemistryEnzymatic Modification

Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3.

Steven P. Smeekens, Anthony Montag, Giju Thomas, +7

Proceedings of the National Academy of Sciences

Missense Mutation of Amylin Gene (S20G) in Japanese NIDDM Patients

Setsuya Sakagashira, Tokio Sanke, Tadashi Hanabusa, +5

Diabetes

Mendelian DisorderGenetic DisorderGeneticsDiabetesInsulin Management +10

Identification and analysis of the gene encoding human PC2, a prohormone convertase expressed in neuroendocrine tissues.

Shinya Ohagi, J LaMendola, Michelle M. LeBeau, +5

Proceedings of the National Academy of Sciences

Molecular BiologyNeuroendocrine TissuesSerine ProteasesInsulin SignalingProtein Expression +20

Sequences of islet amyloid polypeptide precursors of an old world monkey, the pig-tailed macaque (Macaca nemestrina), and the dog (Canis familiaris)

Shinya Ohagi, Masahiro Nishi, Graeme I. Bell, +2

Diabetologia

BiologyMolecular NeurosciencePig-tailed MacaqueCanis FamiliarisOld World Monkey +4

Organization of the human carboxypeptidase E gene and molecular scanning for mutations in Japanese subjects with NIDDM or obesity

Naoko Utsunomiya, Shinya Ohagi, Tokio Sanke, +3

Diabetologia

Metabolic SyndromeGenetic AnalysisMedicineGeneticsProteomics +9

Simple tandem repeat DNA polymorphism in the human glycogen synthase gene is associated with NIDDM in Japanese subjects

Hiroyuki Kuroyama, Tokio Sanke, Shinya Ohagi, +3

Diabetologia

Genetic AnalysisGeneticsGenetic EpidemiologyHuman PolymorphismMolecular Biology +7

Association of the Prohormone Convertase 2 Gene (<i>PCSK2</i>) on Chromosome 20 with NIDDM in Japanese Subjects

Hitomi Yoshida, Shinya Ohagi, Tokio Sanke, +3

Diabetes

Novel putative protein tyrosine phosphatases identified by the polymerase chain reaction

Masahiro Nishi, Shinya Ohagi, Donald F. Steiner

FEBS Letters

Oligonucleotide PrimersMolecular BiologyPolymerase Chain ReactionProtein ExpressionSignaling Pathway +16