Setsuya Sakagashira

Functional Variants in the Glutathione Peroxidase-1 (<i>GPx-1</i>) Gene Are Associated With Increased Intima-Media Thickness of Carotid Arteries and Risk of Macrovascular Diseases in Japanese Type 2 Diabetic Patients

Tohru Hamanishi, Hiroto Furuta, Hisako Kato et al. · Diabetes · 2004 · 222 citations · Full text

Human IAPP–induced pancreatic β cell toxicity and its regulation by autophagy

Nayumi Shigihara, Ayako Fukunaka, Akemi Hara et al. · Journal of Clinical Investigation · 2014 · 170 citations · Full text

Missense Mutation of Amylin Gene (S20G) in Japanese NIDDM Patients

Setsuya Sakagashira, Tokio Sanke, Tadashi Hanabusa et al. · Diabetes · 1996 · 157 citations

Mendelian Disorder, Genetic Disorder, Genetics +12

S20G Mutant Amylin Exhibits Increased in Vitro Amyloidogenicity and Increased Intracellular Cytotoxicity Compared to Wild-Type Amylin

Setsuya Sakagashira, Henry J. Hiddinga, Kayoko Tateishi et al. · American Journal Of Pathology · 2000 · 141 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Vitro Amyloidogenicity +7

Uncoupling Protein 2 Promoter Polymorphism −866G/A Affects Its Expression in β-Cells and Modulates Clinical Profiles of Japanese Type 2 Diabetic Patients

Miyoshi Sasahara, Masahiro Nishi, Hiromichi Kawashima et al. · Diabetes · 2004 · 100 citations · Full text