Giju Thomas

Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin‐like endoprotease.

Andrea Stieneke-Gröber, Martin Vey, Herbert Angliker et al. · The EMBO Journal · 1992 · 647 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +11

Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface.

Sean S. Molloy, Laurel Thomas, Judy K. VanSlyke et al. · The EMBO Journal · 1994 · 494 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

Kex2-like endoproteases PC2 and PC3 accurately cleave a model prohormone in mammalian cells: evidence for a common core of neuroendocrine processing enzymes.

Laurel Thomas, Richard Leduc, Barbara A. Thorne et al. · Proceedings of the National Academy of Sciences · 1991 · 320 citations

Life Sciences, Biochemistry, Endocrinology +17

Proinsulin processing by the subtilisin-related proprotein convertases furin, PC2, and PC3.

Steven P. Smeekens, Anthony Montag, Giju Thomas et al. · Proceedings of the National Academy of Sciences · 1992 · 309 citations

Life Sciences, Biochemistry, Molecular Biology +14

Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant.

Eric Anderson, Laurel Thomas, J. S. Hayflick et al. · Journal of Biological Chemistry · 1993 · 208 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15