J T Holt

An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation.

J T Holt, Robert L. Redner, Arthur W. Nienhuis · Molecular and Cellular Biology · 1988 · 473 citations · Full text

Complementary Oligomer, Molecular Regulation, Immunology +18

Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation.

J T Holt, T. Venkat Gopal, A D Moulton et al. · Proceedings of the National Academy of Sciences · 1986 · 452 citations · Full text

Transcriptional Regulation, Protein Expression, Cell Regulation +13

Development of mammary hyperplasia and neoplasia in MMTV-TGFα transgenic mice

Yasuhisa Matsui, Susan A. Halter, J T Holt et al. · Cell · 1990 · 441 citations

Breast Oncology, Developmental Biology, Mammary Gland Development +10

Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation.

Jennifer A. Pietenpol, J T Holt, Roland Stein et al. · Proceedings of the National Academy of Sciences · 1990 · 396 citations · Full text

C-myc Expression, Immunology, C-myc Gene +18

Double-Strand Break Repair Deficiency and Radiation Sensitivity in BRCA2 Mutant Cancer Cells

Derek W. Abbott, J T Holt, Michael L. Freeman · JNCI Journal of the National Cancer Institute · 1998 · 202 citations · Full text