Concepedia
Statistics
Publications
55
Citations
9.4K
H-Index
39
Active since
1997
Affiliations
Case Western Reserve University(Current)
University School
Harvard University
Beth Israel Deaconess Medical Center
Center for Systems Biology
Derek W. Abbott is an author at Case Western Reserve University specializing in medicine, cell signaling, and signal transduction.
Top concepts
MedicineCell SignalingCell BiologySignal TransductionImmunologyInflammationInnate ImmunityCell DeathNatural SciencesImmune Regulation
Publications per year
1997–2023
Identification of RIP1 kinase as a specific cellular target of necrostatins
Alexei Degterev, Junichi Hitomi, Megan Germscheid et al. · Nature Chemical Biology · 2008 · 2K citations · Full text
Reductive Stress, Specific Cellular Target, Signal Transduction +13
Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis
Joseph K. Rathkey, Junjie Zhao, Zhonghua Liu et al. · Science Immunology · 2018 · 561 citations · Full text
N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis
Mausita Karmakar, Martin Minns, Elyse Noelani Greenberg et al. · Nature Communications · 2020 · 418 citations · Full text
Homophilic CD44 Interactions Mediate Tumor Cell Aggregation and Polyclonal Metastasis in Patient-Derived Breast Cancer Models
Xia Liu, Rokana Taftaf, Madoka Kawaguchi et al. · Cancer Discovery · 2018 · 387 citations
The <i>Mycobacterium tuberculosis</i> serine/threonine kinases PknA and PknB: substrate identification and regulation of cell shape
Choong‐Min Kang, Derek W. Abbott, Sang Tae Park et al. · Genes & Development · 2005 · 384 citations · Full text
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