James M. Nelson

A Specific Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase

David W. Fry, Alan J. Kraker, Amy McMichael et al. · Science · 1994 · 801 citations

Specific Inhibitor, Cancer Research, Signal Transduction +13

PF00299804, an Irreversible Pan-ERBB Inhibitor, Is Effective in Lung Cancer Models with <i>EGFR</i> and <i>ERBB2</i> Mutations that Are Resistant to Gefitinib

Jeffrey A. Engelman, Kreshnik Zejnullahu, Christopher-Michael Gale et al. · Cancer Research · 2007 · 713 citations · Full text

Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor

David W. Fry, Alexander J. Bridges, William A. Denny et al. · Proceedings of the National Academy of Sciences · 1998 · 417 citations

Drug Target, Cell Growth, Chemical Biology +21

Antitumor activity and pharmacokinetic properties of PF-00299804, a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor

Andrea J. Gonzales, Kenneth E. Hook, Irene W. Althaus et al. · Molecular Cancer Therapeutics · 2008 · 220 citations · Full text

Transition Metal-Catalyzed Formation of Phosphorus−Boron Bonds:  A New Route to Phosphinoborane Rings, Chains, and Macromolecules

Hendrik Dorn, Ryan A. Singh, Jason A. Massey et al. · Journal of the American Chemical Society · 2000 · 215 citations

Inorganic Chemistry, Chemical Engineering, Phosphorus−boron Bonds +14