Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally

Huilin Huang, Hengyou Weng, Keren Zhou, +39

Nature

Histone ModificationsChromatinTranscriptional RegulationChromatin StructureChromatin Remodeling +12

Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC

Chenying Li, Lei Dong, Rui Su, +22

Haematologica

High PARP-1 expression predicts poor survival in acute myeloid leukemia and PARP-1 inhibitor and SAHA-bendamustine hybrid inhibitor combination treatment synergistically enhances anti-tumor effects

Xia Li, Chenying Li, Jingrui Jin, +15

EBioMedicine

Enhancement of oral bioavailability and anti-Parkinsonian efficacy of resveratrol through a nanocrystal formulation

Sha Xiong, Wei Liu, Yile Zhou, +7

Asian Journal of Pharmaceutical Sciences

Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes

Yoshihiro Hayashi, Yue Zhang, Asumi Yokota, +38

Cancer Discovery

Tregs dysfunction aggravates postoperative cognitive impairment in aged mice

Yile Zhou, Huihui Ju, Yan Hu, +6

Journal of Neuroinflammation

The high NRF2 expression confers chemotherapy resistance partly through up-regulated DUSP1 in myelodysplastic syndromes

Peipei Lin, Yanling Ren, Xiaomei Yan, +19

Haematologica

6-O-angeloylplenolin exerts neuroprotection against lipopolysaccharide-induced neuroinflammation in vitro and in vivo

Yile Zhou, Yong‐Ming Yan, Siyi Li, +9

Acta Pharmacologica Sinica

InflammationMedicine6-O-angeloylplenolin Exerts NeuroprotectionPharmacologyNeuropharmacology +7

<i>Setd2</i> regulates quiescence and differentiation of adult hematopoietic stem cells by restricting RNA polymerase II elongation

Yile Zhou, Xiaomei Yan, Xiaomin Feng, +13

Haematologica

SETD2 mutations confer chemoresistance in acute myeloid leukemia partly through altered cell cycle checkpoints

Yunzhu Dong, Xinghui Zhao, Xiaomin Feng, +17

Leukemia

Hematological MalignancyTumor BiologyCell Cycle CheckpointsMedicineAcute Myeloid Leukemia +8