Jennifer Bos

Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients

Minke A.E. Rab, Brigitte A. van Oirschot, Jennifer Bos et al. · American Journal of Hematology · 2019 · 75 citations · Full text

Medicine, Hematology, Physiology +17

Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy

Minke A.E. Rab, Jennifer Bos, Brigitte A. van Oirschot et al. · Blood · 2021 · 45 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

One-year safety and efficacy of mitapivat in sickle cell disease: follow-up results of a phase 2, open-label study

Myrthe J. van Dijk, Minke A.E. Rab, Brigitte A. van Oirschot et al. · Blood Advances · 2023 · 29 citations · Full text

Medicine, Hematology, Pharmacology +12

Decreased Activity and Stability of Pyruvate Kinase in Hereditary Hemolytic Anemia: A Potential Target for Therapy By AG-348 (Mitapivat), an Allosteric Activator of Red Blood Cell Pyruvate Kinase

Minke A.E. Rab, Brigitte A. van Oirschot, Stephanie van Straaten et al. · Blood · 2019 · 18 citations

Life Sciences, Biochemistry, Hematology +11

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry

Minke A.E. Rab, Brigitte A. van Oirschot, Jennifer Bos et al. · Journal of Visualized Experiments · 2019 · 16 citations · Full text

Medicine, Cell Biology, Hematology +17