Brigitte A. van Oirschot

Tyrosine kinase activity in breast cancer, benign breast disease, and normal breast tissue.

A. Hennipman, Brigitte A. van Oirschot, J.M.M. Smits et al. · PubMed · 1989 · 106 citations

Medicine, Biochemistry, Oncology +11

The fluid membrane determines mechanics of erythrocyte extracellular vesicles and is softened in hereditary spherocytosis

Daan Vorselen, Susan M. van Dommelen, Raya Sorkin et al. · Nature Communications · 2018 · 104 citations · Full text

Natural Sciences, Biophysics, Cell Biology +17

Ribosomal Protein Mutations Induce Autophagy through S6 Kinase Inhibition of the Insulin Pathway

Harry F.G. Heijnen, Richard van Wijk, Tamara C. Pereboom et al. · PLoS Genetics · 2014 · 79 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

AG-348 (Mitapivat), an allosteric activator of red blood cell pyruvate kinase, increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes

Minke A.E. Rab, Brigitte A. van Oirschot, Penelope A. Kosinski et al. · Haematologica · 2020 · 78 citations · Full text

Life Sciences, Biochemistry, Physiology +16

Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients

Minke A.E. Rab, Brigitte A. van Oirschot, Jennifer Bos et al. · American Journal of Hematology · 2019 · 75 citations · Full text

Medicine, Hematology, Physiology +17