Sudhir M. Hande

Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-<i>N</i>-methylpyridine-2-carboxamide (AZD5305): A PARP1–DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs

Jeffrey W. Johannes, Amber Balazs, Derek Barratt et al. · Journal of Medicinal Chemistry · 2021 · 140 citations · Full text

Life Sciences, Medicinal Chemistry, Oncology +13

Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist

James S. Scott, Amber Balazs, Bernard Barlaam et al. · Journal of Medicinal Chemistry · 2020 · 111 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of AZD4573, a Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement for the Treatment of Hematological Malignancies

Bernard Barlaam, Robert Casella, Justin Cidado et al. · Journal of Medicinal Chemistry · 2020 · 104 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Total synthesis of aspergillide B and structural discrepancy of aspergillide A

Sudhir M. Hande, Jun’ichi Uenishi · Tetrahedron Letters · 2008 · 62 citations

Life Sciences, Chemistry, Microbiology +14

An Efficient Synthesis of 2- and 2,6-Substituted Piperidines Using Pd^II-Catalyzed 1,3-Chirality Transfer Reaction

Sudhir M. Hande, Nobuyuki Kawai, Jun’ichi Uenishi · The Journal of Organic Chemistry · 2008 · 62 citations

Natural Sciences, Chemistry, Catalysis +9