Lynda Cook

2-Aminothiazole as a Novel Kinase Inhibitor Template. Structure−Activity Relationship Studies toward the Discovery of <i>N</i> -(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (Dasatinib, BMS-354825) as a Potent <i>pan</i> -Src Kinase Inhibitor

Jagabandhu Das, Ping Chen, Derek Norris et al. · Journal of Medicinal Chemistry · 2006 · 400 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Development of an Evidence-Based List of Noncytotoxic Vesicant Medications and Solutions

Lisa A. Gorski, Marc Stranz, Lynda Cook et al. · Journal of Infusion Nursing · 2017 · 58 citations

Pharmacy, Pharmacy Practice, Drug Delivery +16

Acyl Guanidine Inhibitors of β-Secretase (BACE-1): Optimization of a Micromolar Hit to a Nanomolar Lead via Iterative Solid- and Solution-Phase Library Synthesis

Samuel W. Gerritz, Weixu Zhai, Shuhao Shi et al. · Journal of Medicinal Chemistry · 2012 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Targeting the MraY and MurG bacterial enzymes for antimicrobial therapeutic intervention

Laura E. Zawadzke, Ping Wu, Lynda Cook et al. · Analytical Biochemistry · 2003 · 48 citations

Pharmacy, Microbiology, Pharmacology +14

Evidence for multiple condensing enzymes in rat hepatic microsomes catalyzing the condensation of saturated, monounsaturated, and polyunsaturated acyl coenzyme A.

M.R.N. Prasad, Mahmoud N. Nagi, Daniéle Ghesquier et al. · Journal of Biological Chemistry · 1986 · 33 citations · Full text

Life Sciences, Biochemistry, Nutritional Sciences +14