Bryan Koci

Blockade of Human Cardiac Potassium Channel Human Ether-a-go-go-Related Gene (HERG) by Macrolide Antibiotics

Walter A. Volberg, Bryan Koci, Wei-guo Su et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 152 citations

Medicine, Cardiology, Pharmacology +15

Novel Potent Human Ether-à-Go-Go-Related Gene (hERG) Potassium Channel Enhancers and Their in Vitro Antiarrhythmic Activity

Jun Zhou, Corinne E. Augelli‐Szafran, Jenifer A. Bradley et al. · Molecular Pharmacology · 2005 · 133 citations

Medicine, Medicinal Chemistry, Pharmacology +17

A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm

Bradley J. Ridder, Derek J. Leishman, Matthew Bridgland‐Taylor et al. · Toxicology and Applied Pharmacology · 2020 · 48 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

Optimization of TopoIV Potency, ADMET Properties, and hERG Inhibition of 5-Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with <i>In Vivo</i> Efficacy against MRSA

Yanran Lu, Sandip Vibhute, Linsen Li et al. · Journal of Medicinal Chemistry · 2021 · 37 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Myocardial Contrast Echocardiography Can Be Used to Assess the Microvascular Response to Vascular Endothelial Growth Factor-121

Flordeliza S. Villanueva, Judith A. Abraham, George F. Schreiner et al. · Circulation · 2002 · 35 citations · Full text

Medicine, Cardiology, Pharmacology +13