Yanran Lu

A ribose-functionalized NAD+ with unexpected high activity and selectivity for protein poly-ADP-ribosylation

Xiaonan Zhang, Qinqin Cheng, Jingwen Chen et al. · Nature Communications · 2019 · 40 citations · Full text

Optimization of TopoIV Potency, ADMET Properties, and hERG Inhibition of 5-Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with <i>In Vivo</i> Efficacy against MRSA

Yanran Lu, Sandip Vibhute, Linsen Li et al. · Journal of Medicinal Chemistry · 2021 · 35 citations · Full text

1,3-Dioxane-Linked Bacterial Topoisomerase Inhibitors with Enhanced Antibacterial Activity and Reduced hERG Inhibition

Linsen Li, Antony A. Okumu, Sheri Nolan et al. · ACS Infectious Diseases · 2019 · 31 citations

Dioxane-Linked Amide Derivatives as Novel Bacterial Topoisomerase Inhibitors against Gram-Positive <i>Staphylococcus aureus</i>

Yanran Lu, Jonathan L. Papa, Sheri Nolan et al. · ACS Medicinal Chemistry Letters · 2020 · 23 citations · Full text

Novel bacterial topoisomerase inhibitors derived from isomannide

Antony A. Okumu, Yanran Lu, Sheri Dellos-Nolan et al. · European Journal of Medicinal Chemistry · 2020 · 13 citations · Full text

Medicine, Antimicrobial Chemotherapy, Antimicrobial Compound +3