Antony A. Okumu

Optimization of TopoIV Potency, ADMET Properties, and hERG Inhibition of 5-Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with <i>In Vivo</i> Efficacy against MRSA

Yanran Lu, Sandip Vibhute, Linsen Li et al. · Journal of Medicinal Chemistry · 2021 · 35 citations · Full text

1,3-Dioxane-Linked Bacterial Topoisomerase Inhibitors with Enhanced Antibacterial Activity and Reduced hERG Inhibition

Linsen Li, Antony A. Okumu, Sheri Nolan et al. · ACS Infectious Diseases · 2019 · 31 citations

Stereochemical Definition of the Natural Product (6<i>R</i>,10<i>R</i>,13<i>R</i>, 14<i>R</i>,16<i>R</i>,17<i>R</i>,19<i>S</i>,20<i>S</i>,21<i>R</i>,24<i>S</i>,25<i>S</i>,28<i>S</i>,30<i>S</i>,32<i>R</i>,33<i>R</i>,34<i>R</i>,36<i>S</i>,37<i>S</i>,39<i>R</i>)‐Azaspiracid‐3 by Total Synthesis and Comparative Analyses

Nathaniel T. Kenton, Daniel Adu‐Ampratwum, Antony A. Okumu et al. · Angewandte Chemie International Edition · 2017 · 22 citations

Bioorganic Chemistry, Toxinology, Chemical Biology +18

Synthesis and anti-staphylococcal activity of novel bacterial topoisomerase inhibitors with a 5-amino-1,3-dioxane linker moiety

Linsen Li, Antony A. Okumu, Sheri Dellos-Nolan et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 18 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +10

Synthesis of the C22–C40 Domain of the Azaspiracids

Zhigao Zhang, Yong Chen, Daniel Adu‐Ampratwum et al. · Organic Letters · 2016 · 16 citations