Patrick Roussel

Optimization of 6,6-dimethyl pyrrolo[3,4-c]pyrazoles: Identification of PHA-793887, a potent CDK inhibitor suitable for intravenous dosing

Maria Gabriella Brasca, Clara Albanese, Rachele Alzani et al. · Bioorganic & Medicinal Chemistry · 2010 · 62 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +9

Crystallographic Analysis of Bacterial Signal Peptidase in Ternary Complex with Arylomycin A₂ and a β-Sultam Inhibitor

Chuanyun Luo, Patrick Roussel, Jürg Dreier et al. · Biochemistry · 2009 · 46 citations

Bacterial Signal Peptidase, Antimicrobial Drug Discovery, Protein Assembly +14

Identification of Potent Pyrazolo[4,3-<i>h</i>]quinazoline-3-carboxamides as Multi-Cyclin-Dependent Kinase Inhibitors

Gabriella Traquandi, Marina Ciomei, Dario Ballinari et al. · Journal of Medicinal Chemistry · 2010 · 40 citations · Full text

Compound 59, Molecular Pharmacology, Medicinal Chemistry +14

A linker for amidines in solid phase synthesis

Patrick Roussel, Mark Bradley, Ian Matthews et al. · Tetrahedron Letters · 1997 · 38 citations

Organic Chemistry, Solid Phase Synthesis, Synthesis Method +2

Inhibition of the tissue factor/factor VIIa complex — Lead optimisation using combinatorial chemistry

Patrick Roussel, Mark Bradley, Peter D. Kane et al. · Tetrahedron · 1999 · 29 citations

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +9