G. N. HENDERSON

Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study

Robinder G. Khemani, Lincoln Smith, Yolanda M. López‐Fernández et al. · The Lancet Respiratory Medicine · 2018 · 423 citations · Full text

Medicine, Child Health, Pediatrics +12

Clinical pharmacology and toxicology of dichloroacetate.

Peter W. Stacpoole, G. N. HENDERSON, Margaret O. James · Environmental Health Perspectives · 1998 · 141 citations · Full text

Pharmacy, Environmental Sciences, Toxicology +17

Glutathione-dependent conversion to glyoxylate, a major pathway of dichloroacetate biotransformation in hepatic cytosol from humans and rats, is reduced in dichloroacetate-treated rats.

Margaret O. James, Rachel Cornett, Zimeng Yan et al. · PubMed · 1997 · 54 citations

Life Sciences, Biochemistry, Cellular Metabolism +10

Pharmacokinetics and pharmacodynamics of dichloroacetate in children with lactic acidosis due to severe malaria

Sanjeev Krishna, Tsiri Agbenyega, Brian Angus et al. · QJM · 1995 · 43 citations

Medicine, Pharmacokinetics, Pharmacology +15

Pharmacokinetics and metabolism of [14C]dichloroacetate in male Sprague-Dawley rats. Identification of glycine conjugates, including hippurate, as urinary metabolites of dichloroacetate.

Margaret O. James, Zimeng Yan, Rachel Cornett et al. · PubMed · 1998 · 40 citations

Pharmacy, Pharmacokinetics, Pharmacology +9