Tumor Suppressor LATS1 Is a Negative Regulator of Oncogene YAP

Yawei Hao, Alex Chun, Kevin J. Cheung, +2

Journal of Biological Chemistry

Cell DeathCancer BiologyTumor BiologySignaling PathwayLats Tumor Suppressor +17

Taxol Resistance in Breast Cancer Cells Is Mediated by the Hippo Pathway Component TAZ and Its Downstream Transcriptional Targets<i>Cyr61</i>and<i>CTGF</i>

Dulcie Lai, King Ching Ho, Yawei Hao, +1

Cancer Research

Breast OncologyCancer BiologyTumor BiologySignaling PathwayCell Regulation +14

The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1

Helena J. Janse van Rensburg, Taha Azad, Ling Min, +7

Cancer Research

LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1

Xiaolong Yang, Kuan-Ping Yu, Yawei Hao, +4

Nature Cell Biology

MedicineReceptor Tyrosine KinaseImmunologyTumor SuppressorCancer Biology +3

Human BAG-1/RAP46 protein is generated as four isoforms by alternative translation initiation and overexpressed in cancer cells

Xiaolong Yang, Garry Chernenko, Yawei Hao, +4

Oncogene

Human Bag-1/rap46 ProteinAlternative Translation InitiationProtein FoldingMedicineMolecular Biology +8

A gain-of-functional screen identifies the Hippo pathway as a central mediator of receptor tyrosine kinases during tumorigenesis

Taha Azad, Kazem Nouri, Helena J. Janse van Rensburg, +8

Oncogene

Hippo PathwaySignal TransductionSignaling PathwayMolecular PathwayReceptor Tyrosine Kinase +8

Molecular characterization of human homologs of yeast MOB1

Annabelle Chow, Yawei Hao, Xiaolong Yang

International Journal of Cancer

Systems BiologySignaling PathwayCell RegulationGeneticsHmob Mrnas Expression +11

PI3K Positively Regulates YAP and TAZ in Mammary Tumorigenesis Through Multiple Signaling Pathways

Yulei Zhao, Tess Montminy, Taha Azad, +6

Molecular Cancer Research

Identification of Celastrol as a Novel YAP-TEAD Inhibitor for Cancer Therapy by High Throughput Screening with Ultrasensitive YAP/TAZ–TEAD Biosensors

Kazem Nouri, Taha Azad, Ling Min, +6

Cancers

High ThroughputCancer BiologyBiosensor Fusion ProteinsTumor BiologyUltrasensitive Yap/taz–tead Biosensors +18

Hippo Component TAZ Functions as a Co-repressor and Negatively Regulates ΔNp63 Transcription through TEA Domain (TEAD) Transcription Factor

Ivette Valencia-Sama, Yulei Zhao, Dulcie Lai, +3

Journal of Biological Chemistry