Helena J. Janse van Rensburg

The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1

Helena J. Janse van Rensburg, Taha Azad, Yawei Hao et al. · Cancer Research · 2018 · 304 citations

Medicine, Cancer Biology, Oncology +17

A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis

Taha Azad, Helena J. Janse van Rensburg, Elizabeth D. Lightbody et al. · Nature Communications · 2018 · 166 citations · Full text

Life Sciences, Cell Biology, Oncology +17

A gain-of-functional screen identifies the Hippo pathway as a central mediator of receptor tyrosine kinases during tumorigenesis

Taha Azad, Kazem Nouri, Helena J. Janse van Rensburg et al. · Oncogene · 2019 · 77 citations

Life Sciences, Cell Biology, Molecular Biology +16

Identification of Celastrol as a Novel YAP-TEAD Inhibitor for Cancer Therapy by High Throughput Screening with Ultrasensitive YAP/TAZ–TEAD Biosensors

Kazem Nouri, Taha Azad, Helena J. Janse van Rensburg et al. · Cancers · 2019 · 59 citations · Full text

Medicine, Oncology, Pharmacology +14

Deletion of tumor necrosis factor-α ameliorates neurodegeneration in Sandhoff disease mice

Hatem Abo-ouf, Alexander WM Hooper, Elizabeth White et al. · Human Molecular Genetics · 2013 · 58 citations · Full text

Medicine, Neurology, Neuroscience +9