Ai Hosaka

GCH1 mutations in dopa-responsive dystonia and Parkinson’s disease

Hiroyo Yoshino, Kenya Nishioka, Yuanzhe Li et al. · Journal of Neurology · 2018 · 48 citations

Neurodegenerative Diseases, Molecular Neuroscience, Parkinson Disease +8

Neuronal β‐amyloid generation is independent of lipid raft association of β‐secretase BACE1: analysis with a palmitoylation‐deficient mutant

Kazumi Motoki, Hideaki Kume, Akiko Oda et al. · Brain and Behavior · 2012 · 44 citations · Full text

Protein Secretion, Molecular Biology, Amyloid Precursor Protein +18

Amyloid β-protein oligomers upregulate the β-secretase, BACE1, through a post-translational mechanism involving its altered subcellular distribution in neurons

Naomi Mamada, Daisuke Tanokashira, Ai Hosaka et al. · Molecular Brain · 2015 · 37 citations · Full text

LRP1 Downregulates the Alzheimer’s β-Secretase BACE1 by Modulating Its Intraneuronal Trafficking

Daisuke Tanokashira, Kazumi Motoki, Seiji Minegishi et al. · eNeuro · 2015 · 24 citations · Full text

Protein Secretion, Synaptic Transmission, Alzheimer ’ +21

Statins Reduce Amyloid β-Peptide Production by Modulating Amyloid Precursor Protein Maturation and Phosphorylation Through a Cholesterol-Independent Mechanism in Cultured Neurons

Ai Hosaka, Wataru Araki, Akiko Oda et al. · Neurochemical Research · 2012 · 21 citations

Cultured Neurons, Neurodegenerative Diseases, Molecular Neuroscience +8