Hideaki Kume

Cleft palate and decreased brain γ-aminobutyric acid in mice lacking the 67-kDa isoform of glutamic acid decarboxylase

Hideo Asada, Yuuki Kawamura, Kei Maruyama et al. · Proceedings of the National Academy of Sciences · 1997 · 556 citations

Life Sciences, Neurobiology, Neuroscience +17

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue

Taisuke Tomita, Kei Maruyama, Takaomi C. Saido et al. · Proceedings of the National Academy of Sciences · 1997 · 385 citations

Life Sciences, Genetics, Molecular Biology +16

Mice Lacking the 65 kDa Isoform of Glutamic Acid Decarboxylase (GAD65) Maintain Normal Levels of GAD67 and GABA in Their Brains but Are Susceptible to Seizures

Hideo Asada, Yuuki Kawamura, Kei Maruyama et al. · Biochemical and Biophysical Research Communications · 1996 · 321 citations

Life Sciences, Neurobiology, Neuroscience +13

Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer

Kazutoshi Fujita, Hideaki Kume, Kyosuke Matsuzaki et al. · Scientific Reports · 2017 · 174 citations · Full text

Medicine, Biochemistry, Urology +17

Discovery of Colorectal Cancer Biomarker Candidates by Membrane Proteomic Analysis and Subsequent Verification using Selected Reaction Monitoring (SRM) and Tissue Microarray (TMA) Analysis

Hideaki Kume, Satoshi Muraoka, Takahisa Kuga et al. · Molecular & Cellular Proteomics · 2014 · 129 citations · Full text

Life Sciences, Molecular Biology, Oncology +17