Discovery of Colorectal Cancer Biomarker Candidates by Membrane Proteomic Analysis and Subsequent Verification using Selected Reaction Monitoring (SRM) and Tissue Microarray (TMA) Analysis

Hideaki Kume, Satoshi Muraoka, Takahisa Kuga, +12

Molecular & Cellular Proteomics

EngineeringPathologyQuantitative Proteomic TechnologyProteomic TechnologyBiomarker Discovery +17

Identification of Missing Proteins in the neXtProt Database and Unregistered Phosphopeptides in the PhosphoSitePlus Database As Part of the Chromosome-Centric Human Proteome Project

Takashi Shiromizu, Jun Adachi, Shio Watanabe, +4

Journal of Proteome Research

Src Signaling Regulates Completion of Abscission in Cytokinesis through ERK/MAPK Activation at the Midbody

Kousuke Kasahara, Yuji Nakayama, Yoshimi Nakazato, +3

Journal of Biological Chemistry

A Strategy for Large-Scale Phosphoproteomics and SRM-Based Validation of Human Breast Cancer Tissue Samples

Ryohei Narumi, Tatsuo Murakami, Takahisa Kuga, +12

Journal of Proteome Research

Breast OncologyMolecular BiologyProteomic TechnologyCancer DetectionBreast Imaging +21

Rapid trafficking of c-Src, a non-palmitoylated Src-family kinase, between the plasma membrane and late endosomes/lysosomes

Kousuke Kasahara, Yuji Nakayama, Akio Kihara, +6

Experimental Cell Research

Signal TransductionPlasma MembraneCell SignalingNatural SciencesCell Trafficking +13

Involvement of Golgi-associated Lyn tyrosine kinase in the translocation of annexin II to the endoplasmic reticulum under oxidative stress

Daisuke Matsuda, Yuji Nakayama, Shinya Horimoto, +4

Experimental Cell Research

MitophagySignal TransductionBiochemistryAnnexin IiEndocytic Pathway +8

Increased expression of sorcin is associated with multidrug resistance in leukemia cells via up-regulation of MDR1 expression through cAMP response element-binding protein

Nobuyuki Yamagishi, Ryota Nakao, Rumi Kondo, +5

Biochemical and Biophysical Research Communications

Drug Resistance AnalysisMdr1 ExpressionMedicineImmunologyMultidrug Resistance +6

A novel mechanism of keratin cytoskeleton organization through casein kinase Iα and FAM83H in colorectal cancer

Takahisa Kuga, Hideaki Kume, Naoko Kawasaki, +7

Journal of Cell Science

FAM83H and casein kinase I regulate the organization of the keratin cytoskeleton and formation of desmosomes

Takahisa Kuga, Mitsuho Sasaki, Toshinari Mikami, +9

Scientific Reports

Nuclear localization of Src-family tyrosine kinases is required for growth factor-induced euchromatinization

Akinori Takahashi, Yuuki Obata, Yasunori Fukumoto, +7

Experimental Cell Research

ChromatinCell RegulationChromatin RemodelingSrc-family Tyrosine KinasesReceptor Tyrosine Kinase +8