Benjamin L. Barthel

Genetic ablation of inducible nitric oxide synthase decreases mouse lung tumorigenesis.

Lori R. Kisley, Bradley S. Barrett, Alison K. Bauer et al. · PubMed · 2002 · 121 citations

Medicine, Cancer Biology, Oncology +14

Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs

Da Xiao, Deshi Shi, Dongfang Yang et al. · Biochemical Pharmacology · 2012 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Design, Synthesis, and Preliminary Evaluation of Doxazolidine Carbamates as Prodrugs Activated by Carboxylesterases

David J. Burkhart, Benjamin L. Barthel, Glen C. Post et al. · Journal of Medicinal Chemistry · 2006 · 48 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Doxazolidine, a Proposed Active Metabolite of Doxorubicin That Cross-links DNA

Glen C. Post, Benjamin L. Barthel, David J. Burkhart et al. · Journal of Medicinal Chemistry · 2005 · 45 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Identification of Human Intestinal Carboxylesterase as the Primary Enzyme for Activation of a Doxazolidine Carbamate Prodrug

Benjamin L. Barthel, Renee C. Torres, Janice L. Hyatt et al. · Journal of Medicinal Chemistry · 2008 · 37 citations

Medicine, Medicinal Chemistry, Pharmacology +15