Dongfang Yang

Anti-Influenza Prodrug Oseltamivir Is Activated by Carboxylesterase Human Carboxylesterase 1, and the Activation Is Inhibited by Antiplatelet Agent Clopidogrel

Deshi Shi, Jian Yang, Dongfang Yang et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 277 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Antiplatelet Agents Aspirin and Clopidogrel Are Hydrolyzed by Distinct Carboxylesterases, and Clopidogrel Is Transesterificated in the Presence of Ethyl Alcohol

Man Tang, Madhu Mukundan, Jian Yang et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 250 citations

Medicine, Biochemistry, Pharmacology +9

Human carboxylesterases HCE1 and HCE2: Ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin

Dongfang Yang, Robin E. Pearce, Xiliang Wang et al. · Biochemical Pharmacology · 2008 · 168 citations · Full text

Life Sciences, Biochemistry, Pharmacology +10

Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation

Yuxin Li, He Zhang, Mingxing Xie et al. · Biochemical Journal · 2002 · 128 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Rat Serum Carboxylesterase

Bingfang Yan, Dongfang Yang, Peter L. Bullock et al. · Journal of Biological Chemistry · 1995 · 86 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8