Concepedia

Antiplatelet Agents Aspirin and Clopidogrel Are Hydrolyzed by Distinct Carboxylesterases, and Clopidogrel Is Transesterificated in the Presence of Ethyl Alcohol

Man Tang, Madhu Mukundan, Jian Yang, Nathan Charpentier, Edward L. LeCluyse, Chris Black, Dongfang Yang, Deshi Shi, Bingfang Yan

Journal of Pharmacology and Experimental Therapeutics · 2006 · 250 citations · 29 references

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29

Platelets in inflammation and atherogenesis

Meinrad Gawaz · Journal of Clinical Investigation · 2005 · 1.5K citations · Full text

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Identification and Biological Activity of the Active Metabolite of Clopidogrel

Pierre Savi, Jean‐Marie Pereillo, Marie-Françoise Uzabiaga et al. · Thrombosis and Haemostasis · 2000 · 748 citations

, , +17

Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma

Bin Li, Meghan Sedlacek, Indumathi Manoharan et al. · Biochemical Pharmacology · 2005 · 532 citations

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Contribution of Hepatic Cytochrome P450 3A4 Metabolic Activity to the Phenomenon of Clopidogrel Resistance

Wei C. Lau, Paul A. Gurbel, Paul B. Watkins et al. · Circulation · 2004 · 485 citations · Full text

, , +17

Structure and Stereochemistry of the Active Metabolite of Clopidogrel

Jean‐Marie Pereillo, Mohamed Maftouh, Alain Andrieu et al. · Drug Metabolism and Disposition · 2002 · 458 citations

, , +17