Addressing overtreatment of screen detected DCIS; the LORIS trial

Adele Francis, Jeremy Thomas, Lesley Fallowfield, +19

European Journal of Cancer

Medical DiagnosticsLoris TrialPoint-of-care TestingDiagnosisMedicine +1

Comparing Breast Cancer Multiparameter Tests in the OPTIMA Prelim Trial: No Test Is More Equal Than the Others

John M.S. Bartlett, Jane Bayani, Andrea Marshall, +17

JNCI Journal of the National Cancer Institute

PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression

Kelly Chiang, Agnieszka Zielińska, Abeer M. Shaaban, +12

Cell Reports

Epigenetic ChangeCancer BiologyTreatment ResistanceEpigeneticsTumor Biology +20

The QuinteT Recruitment Intervention supported five randomized trials to recruit to target: a mixed-methods evaluation

Leila Rooshenas, Lauren J Scott, Jane Blazeby, +98

Journal of Clinical Epidemiology

Management and 5-year outcomes in 9938 women with screen-detected ductal carcinoma in situ: the UK Sloane Project

Alastair M. Thompson, Karen Clements, Shan Cheung, +44

European Journal of Cancer

Screen-detected Ductal CarcinomaSurgical OncologyCancer ScreeningMedicineCancer Management +9

An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment

Marcus Jepson, Daisy Elliott, Carmel Conefrey, +102

Journal of Clinical Epidemiology

Value of Information Analysis of Multiparameter Tests for Chemotherapy in Early Breast Cancer: The OPTIMA Prelim Trial

Peter Hall, Alison Smith, Claire Hulme, +15

Value in Health

Breast OncologyCancer DetectionCancer ScreeningMultiparameter TestsMedicine +10

Low grade Ductal Carcinoma in situ (DCIS): How best to describe it?

Lesley Fallowfield, Lucy Matthews, Adele Francis, +2

The Breast

The radiological features, diagnosis and management of screen-detected lobular neoplasia of the breast: Findings from the Sloane Project

Anthony Maxwell, Karen Clements, David Dodwell, +8

The Breast

Time for a low-risk DCIS trial: harnessing public and patient involvement

Lesley Fallowfield, Adele Francis, Susan Catt, +2

The Lancet Oncology

Primary CarePreventive MedicineTreatment And PreventionLow-risk Dcis TrialPatient Safety +7