Nick Cammack

The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture

Klaus Klumpp, Vincent Lévêque, Sophie Le Pogam et al. · Journal of Biological Chemistry · 2005 · 215 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +15

A Novel Substrate-Based HIV-1 Protease Inhibitor Drug Resistance Mechanism

Monique Nijhuis, Noortje M. van Maarseveen, Stéphane Lastère et al. · PLoS Medicine · 2007 · 167 citations · Full text

Life Sciences, Infectious Diseases, Molecular Genetics +17

The Hepatitis C Virus Replicon Presents a Higher Barrier to Resistance to Nucleoside Analogs than to Nonnucleoside Polymerase or Protease Inhibitors

Matthew F. McCown, Sonal Rajyaguru, Sophie Le Pogam et al. · Antimicrobial Agents and Chemotherapy · 2008 · 164 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

Characterization of determinants of genotypic and phenotypic resistance to enfuvirtide in baseline and on-treatment HIV-1 isolates

Prakash Sista, Tom Melby, Donna K. Davison et al. · AIDS · 2004 · 154 citations

Life Sciences, Infectious Diseases, Molecular Biology +17

Selection and Characterization of Replicon Variants Dually Resistant to Thumb- and Palm-Binding Nonnucleoside Polymerase Inhibitors of the Hepatitis C Virus

Sophie Le Pogam, Hyunsoon Kang, Seth F. Harris et al. · Journal of Virology · 2006 · 131 citations · Full text

Life Sciences, Molecular Biology, Molecular Pharmacology +16