Neil W. Gibson

Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer

Kai Wang, Junsuo Kan, Siu Tsan Yuen et al. · Nature Genetics · 2011 · 775 citations

Medicine, Genetics, Molecular Genetics +16

Epithelial to Mesenchymal Transition Is a Determinant of Sensitivity of Non–Small-Cell Lung Carcinoma Cell Lines and Xenografts to Epidermal Growth Factor Receptor Inhibition

Stuart Thomson, Elizabeth Buck, Filippo Petti et al. · Cancer Research · 2005 · 672 citations

Life Sciences, Molecular Biology, Oncology +17

Kinetic Analysis of Epidermal Growth Factor Receptor Somatic Mutant Proteins Shows Increased Sensitivity to the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Erlotinib

Kendall D. Carey, Andrew J. Garton, Maria S. Romero et al. · Cancer Research · 2006 · 443 citations

Medicine, Oncology, Pharmacology +16

Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a novel drug with potential as an alternative to dacarbazine.

M. F. G. STEVENS, J A Hickman, S P Langdon et al. · PubMed · 1987 · 390 citations

Medicine, Oncology, Pharmacology +9

NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.

R D Traver, T. Horikoshi, Kathleen D. Danenberg et al. · PubMed · 1992 · 317 citations

Medicine, Biochemistry, Molecular Biology +13