J A Hickman

Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methyl-imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a novel drug with potential as an alternative to dacarbazine.

M. F. G. STEVENS, J A Hickman, S P Langdon et al. · PubMed · 1987 · 390 citations

Antitumor Activity, Pharmacotherapy, Metronomic Chemotherapy +17

The relationships between p53-dependent apoptosis, inhibition of proliferation, and 5-fluorouracil-induced histopathology in murine intestinal epithelia.

D. Mark Pritchard, Christopher S. Potten, J A Hickman · PubMed · 1998 · 126 citations

P53-dependent Apoptosis, 5-Fluorouracil-induced Histopathology, Apoptosis +18

Evidence for reciprocity of bcl-2 and p53 expression in human colorectal adenomas and carcinomas

AJM Watson, AJ Merritt, LS Jones et al. · British Journal of Cancer · 1996 · 124 citations · Full text

Human Colorectal Adenomas, Tumor Biology, Medicine +8

Death from vertebral artery thrombosis in rheumatoid arthritis.

F W Webb, J A Hickman, Daniel Brew · BMJ · 1968 · 92 citations · Full text

Synthesis and biological evaluation of a series of flavones designed as inhibitors of protein tyrosine kinases.

Bernadette D.M. Cunningham, Michael D. Threadgill, Paul W. Groundwater et al. · PubMed · 1992 · 65 citations

Chemoprevention Strategy, Tyrosine Kinase, Immunology +16