Exercise training augments Sirt1-signaling and attenuates cardiac inflammation in D-galactose induced-aging rats

Wei-Kung Chen, Ying-Lan Tsai, Marthandam Asokan Shibu, +7

Aging

AgingCardiometabolic RiskVascular AgingCardiovascular FunctionOxidative Stress +22

17β-Estradiol and/or Estrogen Receptor β Attenuate the Autophagic and Apoptotic Effects Induced by Prolonged Hypoxia Through HIF-1α-Mediated BNIP3 and IGFBP-3 Signaling Blockage

Dennis Jine-Yuan Hsieh, Wei-Wen Kuo, Yi-Ping Lai, +7

Cellular Physiology and Biochemistry

Prostaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon Cancer Cells

Hsi-Hsien Hsu, Yueh-Min Lin, Chia-Yao Shen, +8

International Journal of Molecular Sciences

Pge2 InducesChemoprevention StrategyCell DeathEp4 Signaling PathwaysCancer Biology +15

Tetramethylpyrazine Ameliorated Hypoxia-Induced Myocardial Cell Apoptosis via HIF-1α/JNK/p38 and IGFBP3/BNIP3 Inhibition to Upregulate PI3K/Akt Survival Signaling

Kuan‐Ho Lin, Wei‐Wen Kuo, Ai-Zhi Jiang, +7

Cellular Physiology and Biochemistry

Protective effect of Fisetin against angiotensin II-induced apoptosis by activation of IGF-IR-PI3K-Akt signaling in H9c2 cells and spontaneous hypertension rats

Yeh-Peng Chen, Kalaiselvi Sivalingam, Marthandam Asokan Shibu, +8

Phytomedicine

InflammationHypertensionSpontaneous Hypertension RatsMedicinePhysiology +10

Bioactive Peptide Improves Diet-Induced Hepatic Fat Deposition and Hepatocyte Proinflammatory Response in SAMP8 Ageing Mice

Stanley Dumeus, Marthandam Asokan Shibu, Wan‐Teng Lin, +7

Cellular Physiology and Biochemistry

Moderate exercise training attenuates aging-induced cardiac inflammation, hypertrophy and fibrosis injuries of rat hearts

Po‐Hsiang Liao, Dennis Jine-Yuan Hsieh, Chia‐Hua Kuo, +7

Oncotarget

Attenuation of the LPS-induced, ERK-mediated upregulation of fibrosis-related factors FGF-2, uPA, MMP-2, and MMP-9 by <i>Carthamus tinctorius</i> L in cardiomyoblasts

Chien-Kuo Han, Yun-Chen Tien, Dennis Jine‐Yuan Hsieh, +8

Environmental Toxicology

Novel Target Genes Responsive to Apoptotic Activity by<i>Ocimum gratissimum</i>in Human Osteosarcoma Cells

Chien-Chung Lin, Pei-Yu Chao, Chia-Yao Shen, +4

The American Journal of Chinese Medicine

Human Osteosarcoma CellsChemoprevention StrategyHuman Osteosarcoma U2-osCell DeathPathology +17

Platycodin D Reverses Pathological Cardiac Hypertrophy and Fibrosis in Spontaneously Hypertensive Rats

Yuan-Chuan Lin, Yu‐Chen Lin, Wei‐Wen Kuo, +7

The American Journal of Chinese Medicine

HypertensionHeart FailureCardiovascular PharmacologyPathologyCardiovascular Function +14