Benjamin G. Tehan - Concepedia

Author

Benjamin G. Tehan

Also Known As

Benjamin G Tehan, Benjamin G. Tehan, Benjamin Gerald Tehan, Benjamin Tehan, Benjamin G. Tehan, Tehan, Benjamin G, Tehan, Benjamin, 1970-

Publications

2.2K

Citations

H-Index

Concepts

All Affiliations

Heptares Therapeutics (United Kingdom)Monash University Swinburne University of Technology Hertfordshire Community NHS Trust

About

Benjamin G. Tehan is an author at Heptares Therapeutics (United Kingdom) specializing in medicine, biochemistry, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	11	1.1K
2	Biochemistry	8	8	991
3	Natural Sciences	7	7	973
4	Engineering	4	4	301
5	Social Sciences	1	1	10

Benjamin G. Tehan

Publications

1.9K

Citations

H-Index

Page 1

	Year	Citations
Discovery of 1,2,4-Triazine Derivatives as Adenosine A<sub>2A</sub> Antagonists using Structure Based Drug Design Miles Congreve, Stephen P. Andrews, A.S. Dore, Journal of Medicinal Chemistry Combinatorial ChemistryCompound 4KPharmacotherapyPharmaceutical ChemistryMolecular Pharmacology	2012	301
Structural insight into allosteric modulation of protease-activated receptor 2 R.K. Cheng, Cédric Fiez-Vandal, Oliver Schlenker, Nature Signal TransductionBiochemistryG Protein-coupled ReceptorNatural SciencesMedicine	2017	246
Biophysical Fragment Screening of the β <sub>1</sub> -Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design J.A. Christopher, Jason Brown, A.S. Dore, Journal of Medicinal Chemistry	2013	157
Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu <sub>5</sub> Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile) J.A. Christopher, Sarah J. Aves, K.A. Bennett, Journal of Medicinal Chemistry	2015	156
Estimation of pKa Using Semiempirical Molecular Orbital Methods. Part 1: Application to Phenols and Carboxylic Acids. Benjamin G. Tehan, Edward J. Lloyd, Margaret G. Wong, Quantitative Structure-Activity Relationships Carboxylic AcidsEngineeringChemical AnalysisBiochemistryNatural Sciences	2002	120
Comparisons of the Hbv and HIV Polymerase, and Antiviral Resistance Mutations Angeline Bartholomeusz, Benjamin G. Tehan, David K. Chalmers Antiviral Therapy Viral ReplicationImmunologyMolecular BiologyChronic Hepatitis BAntiviral Drug	2004	120
Biophysical Mapping of the Adenosine A<sub>2A</sub> Receptor Andrei Zhukov, Stephen P. Andrews, James C. Errey, Journal of Medicinal Chemistry Molecular PharmacologySignal TransductionMolecular PhysiologyBiochemistryBiophysical Mapping	2011	114
From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer’s disease Alastair Brown, Sophie J. Bradley, Fiona H. Marshall, Cell Molecular PharmacologyNeurodegenerative DiseasesAlzheimer's DiseaseMedicineMechanism Of Action	2021	87
High end GPCR design: crafted ligand design and druggability analysis using protein structure, lipophilic hotspots and explicit water networks Jonathan S. Mason, Andrea Bortolato, Dahlia R. Weiss, In Silico Pharmacology Chemical BiologyMedicinal ChemistryExplicit Water NetworksBiochemistryDrug Design	2013	86
Estimation of pKa Using Semiempirical Molecular Orbital Methods. Part 2: Application to Amines, Anilines and Various Nitrogen Containing Heterocyclic Compounds. Benjamin G. Tehan, Edward J. Lloyd, Margaret G. Wong, Quantitative Structure-Activity Relationships Frontier Electron TheoryEngineeringBiochemistryChemical AnalysisNatural Sciences	2002	80

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