NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components

Sarah Doyle, Matthew Campbell, Ema Ozaki, +10

Nature Medicine

InflammationOcular DiseaseAutoimmune DiseaseOphthalmologyAge-related Diseases +9

IL-18 Attenuates Experimental Choroidal Neovascularization as a Potential Therapy for Wet Age-Related Macular Degeneration

Sarah Doyle, Ema Ozaki, Kiva Brennan, +14

Science Translational Medicine

Targeted suppression of claudin-5 decreases cerebral oedema and improves cognitive outcome following traumatic brain injury

Matthew Campbell, Finnian Hanrahan, Oliviero L. Gobbo, +14

Nature Communications

IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment

Josy Augustine, Sofia Pavlou, Imran Ali, +6

Journal of Neuroinflammation

Interleukin‐33 regulates tissue remodelling and inhibits angiogenesis in the eye

Sofia Theodoropoulou, David A. Copland, Jian Liu, +6

The Journal of Pathology

Ocular DiseaseImmune RegulationImmunologyAge-related Macular DegenerationRetinal Therapies +15

Dysregulated claudin-5 cycling in the inner retina causes retinal pigment epithelial cell atrophy

Natalie Hudson, Lucia Celkova, A. Hopkins, +17

JCI Insight

Ocular DiseaseImmunologyAge-related Macular DegenerationRetinaClaudin-5 Cycling +16

Plasmonics-enhanced and optically modulated delivery of gold nanostars into brain tumor

Hsiangkuo Yuan, Christy Wilson, Jun Xia, +11

Nanoscale

IL-18 Immunotherapy for Neovascular AMD: Tolerability and Efficacy in Nonhuman Primates

Sarah Doyle, Francisco J. López, Lucia Celkova, +11

Investigative Ophthalmology & Visual Science

Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration

Kelly Mulfaul, Ema Ozaki, Nilisha Fernando, +11

Cell Reports

SARM1 deficiency promotes rod and cone photoreceptor cell survival in a model of retinal degeneration

Ema Ozaki, Luke Gibbons, Nuno Neto, +8

Life Science Alliance