Immunohistochemical Evidence for an Increased Oxidative Stress and Carbonyl Modification of Proteins in Diabetic Glomerular Lesions

Daisuke Suzuki, Toshio Miyata, Noboru Saotome, +8

Journal of the American Society of Nephrology

Renoprotective Properties of Angiotensin Receptor Blockers beyond Blood Pressure Lowering

Yuko Izuhara, Masaomi Nangaku, Reiko Inagi, +5

Journal of the American Society of Nephrology

Inhibition of Plasminogen Activator Inhibitor-1

Yuko Izuhara, Satoru Takahashi, Masaomi Nangaku, +6

Arteriosclerosis Thrombosis and Vascular Biology

Advanced glycation and lipidoxidation of the peritoneal membrane: Respective roles of serum and peritoneal fluid reactive carbonyl compounds

T Miyata, Katsunori Horie, Yasuhiko Ueda, +7

Kidney International

BiochemistryLipid PeroxidationPhysiologyGlycobiologyRespective Roles +2

A Novel Class of Prolyl Hydroxylase Inhibitors Induces Angiogenesis and Exerts Organ Protection Against Ischemia

Masaomi Nangaku, Yuko Izuhara, Shunya Takizawa, +7

Arteriosclerosis Thrombosis and Vascular Biology

A Novel Inhibitor of Plasminogen Activator Inhibitor-1 Provides Antithrombotic Benefits Devoid of Bleeding Effect in Nonhuman Primates

Yuko Izuhara, Nagahisa Yamaoka, Hidehiko Kodama, +6

Journal of Cerebral Blood Flow & Metabolism

Novel InhibitorPharmacotherapyNonhuman PrimatesInflammationThrombosis +17

Mechanism of the Inhibitory Effect of OPB-9195 [(±)-2-Isopropylidenehydrazono-4-oxo-thiazolidin-5-ylacetanilide] on Advanced Glycation End Product and Advanced Lipoxidation End Product Formation

Toshio Miyata, Yasuhiko Ueda, Koichi Asahi, +5

Journal of the American Society of Nephrology

Effect of dwell time on carbonyl stress using icodextrin and amino acid peritoneal dialysis fluids

Yasuhiko Ueda, Toshio Miyata, Éric Goffin, +7

Kidney International

Dwell TimeBiochemistryPeritoneal Dialysis FluidsDialysis TherapyNephrology +1

In a type 2 diabetic nephropathy rat model, the improvement of obesity by a low calorie diet reduces oxidative/carbonyl stress and prevents diabetic nephropathy

Masaomi Nangaku, Yuko Izuhara, Nobuteru Usuda, +6

Nephrology Dialysis Transplantation

Overexpression of the serpin megsin induces progressive mesangial cell proliferation and expansion

Toshio Miyata, Reiko Inagi, Masaomi Nangaku, +9

Journal of Clinical Investigation